PHILADELPHIA — What a difference a week makes.

The Nationals’ lineup Tuesday night didn’t feature Luis García Jr., Curtis Mead or James Wood. García and Mead were both traded in an effort to beef up the pitching depth throughout the organization, and Wood was placed on the 10-day injured list with a mild oblique strain.

The offense has thrived with a next-man-up mentality, but that’s hard to replicate without the trio of players missing Tuesday. The Nationals were shutout by the Phillies, 5-0.

As the team is in the midst of its worst stretch of the season, the Nationals need their supporting players to step into starring roles and seize those opportunities. Over their seven-game losing streak, the Nationals (55-60) scored three runs or fewer six times.

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“At least over the next 10 days, it’s an opportunity for other guys to step up,” Butera said before the game. “We need to have the next-man-up mentality.”

Among qualified Washington hitters, Daylen Lile’s .715 on-base-plus-slugging percentage is the second-highest after Wood and fellow All-Star CJ Abrams. Injuries happen over the course of a 162-game season, but the Nationals had been pretty fortunate until Wood’s injury — Drew Millas is the only other position player to be on the injured list this season.

Resilience has been a hallmark for the Nationals. Their ability to consistently bounce back defined their first half. Butera pointed out that most teams have dealt with extended absences from key contributors, and now they’re no different.

“We can’t act like: ‘Oh, look at us ... we lost this guy and this guy’” Butera said. “Every team has gone through it. Every team is going to go through it. Now it’s up to the resiliency you mentioned. It’s up to somebody picking up the slack, and looking at this like an opportunity to showcase their skills.”

Abrams’ second-inning leadoff double immediately got the Nationals a runner in scoring position. But he remained stationed at second base after two flyouts and a groundout ended the top half of the inning.

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With one out in the fourth, Brady House hit a line-drive single and advanced to second on a passed ball. Abrams, the team’s best hitter with runners in scoring position, was called out on strikes, but Harry Ford’s two-out walk kept the inning alive. Jacob Young struck out to end the scoring threat.

In the seventh, Ford hit a one-run double to again give the Nationals a scoring opportunity. But they stranded him like they have most of the time over the past two weeks.

The Nationals were 0-for-11 with runners in scoring position, and are 3-for-46 in those situations on eight-game road trip. They’ve struggled to cash in runs at the level they did earlier in the season.